Dr. Chris travels to Costa Rica to help a sloth suffering from a life-threatening injury; he captures and helps a capuchin monkey with an unidentified skin disease; Chris also treats dogs with a mite infestation at Territorio Zaguates.

In Tasmania, endangered Tasmanian Devils have been dying from a rare form of cancer, and Dr. Christ must help save them from extinction; he also helps rescue an injured pademelon, then he helps wombats suffering from severe cases of mange.

Dr. Chris visits Namibia where he works with the cheetah population at the N/a'an Ku Se Wildlife Sanctuary; a baboon that may have brain trauma; meerkats get a health check before releasing them back to the wild.

Returning home to Australia, Chris investigates a deadly disease that's killing koalas; keep in the remote Northern Territory, he helps an aboriginal town that is overrun by dogs, a kangaroo with an infection.

Dr. Chris travels to Vietnam where he must perform surgery on two endangered turtles; Chris works with an adorable langur and very ill baby loris; a group of smuggled Pangolins are on the bring of death from hypothermia.

Dr. Chris saves fur seals off the coast of Australia who has been entangled in a fishing wire; Chris travels to Fiji to tag bull sharks who are being fished in a local river; he helps a badly injured pig who was attacked by dogs.

Dr. Chris is called o South Africa where he must perform surgery on a trio of lionesses; he helps de-horn an endangered white rhino to keep the poachers away and races to replace the tracking collar on a female elephant.

Dr. Chris Brown heads to Thailand to give medical attention to endangered Asian elephants; the release of two gibbons; a difficult surgery on a dog rescued from a life-threatening situation.