aimless-46 Dude this movie was HILARIOUS!!! its about this dude, and he couldn't find his car.Sorry wrong movie but same intellectual level. Like the teen comedy "Dude, Where's My Car", "LD 50 Lethal Dose" bravely seeks the lowest rung of its genre's (in this case sci-fi, sort of) intelligence ladder. The only positive outcome is the possibility that first-time writer Matthew McGuchan is now ashamed enough about his sad screenplay to seek a permanent career in the food service industry.Basically "LD 50 Lethal Dose" is what you would have if someone tried to remake 1970's "The Andromeda Strain" under a lot of budget constraints. Speaking of budgets, can anyone find the $8 Million allocated to this movie? Very little of even that modest amount makes it to the screen. And speaking of mysteries, how did they manage to find that kind of financing for this turkey?"LD 50 Lethal Dose" has the same production design concept as the two "Saw" movies and "The Hole"; find an abandoned industrial building, go inside, and roll camera. But even though this particular claustrophobic set has more potential than the others, the finished product is not even remotely in their league. A few artsy interior shots can't salvage a premise this lame or a script this staggeringly bad.If you enjoy life on the bottom rung of the sci-fi ladder you would be better served by something that at least has some innate charm (insert "Godzilla" here). "LD 50 Lethal Dose" might have eventual parody potential but I am not masochistic enough to watch it again for confirmation.Then again, what do I know? I'm only a child.

slayrrr666 "LD 50: Lethal Dose" isn't that bad of an animal rights horror film.**SPOILERS**Several members of an animal rights activist group, Gary, (Ross McCall) Danny, (Leo Bill) Matt, (Tom Hardy) Helen, (Katherine Towne) and Justin (Toby Fischer) raid a chemical lab where animals are being held and release the animals, but when Gary is captured by their security system, the others scatter. One year later, Gary is in prison and the rest of the gang is getting worried that the new experiment Gary signed up for is bad news. When they bring their friends Louise (Melanie Brown) and Vaughn (Philip Winchester) in to help out, Helen joins in only to help get rid of the nightmares she's having about Gary. Last minute addition Spook (Stephan Lord) also arrives, and he, Vaughn, Louise, Helen, Danny, Matt and Justin head over to the lab where they believe Gary was taken for the experiments. Exploring the huge complex, they can tell that something isn't right in the facility, and it starts to freak them out. After some exploring, things really start to get freaky, and now the slowly dwindling group has to get out of the research facility alive.The Good News: Perhaps the best part of the film is the design of the facility the characters become trapped in. It's large in design, but the cramped rooms and long, barren hallways set up the mood perfectly. This film has tons of atmosphere, with the drab, gray walls and miles of cables running alone that really help out as well. Combine this with some choice lighting and you get a movie loaded with suspense and tons of interesting set pieces. It was also nice to see so much bloodletting in this film, as well. We get lots of the red stuff, in the form of chopped off arms, a very bloody knife stabbing, a couple of nosebleeds, and some head melts onto cement and then peeled away with skin spreading back too. There's more gore in the film, pleasing any real gore fan. Don't be too surprised at the mention of the nosebleeds in the earlier part of the film, they are far bloodier than you can think. One last thing about the gore: don't expect Fulci/Romero style gore in here. Think instead of supernatural artery blood flow. Nothing just trickles out, this stuff gushes out in spades. The special effects in the film are also first rate. To see people being hurled into walls propelled by flashing electrical bolts, or the fate of the whole crew at the end, this is full of great special effects. Even better still, the film sets up the last half of it as a series of chilling set-pieces and non-stop shocks, all because the middle half is so brilliantly put together. The suspense is incredibly unnerving, and following the group as they explore the facility, unsure of what they're going to find. This is a great attribute for a film.The Bad News: Those going in expecting a killer creature film, like I did, will be disappointed by what I have to say next, so if you are planning on watching the film, don't read the next few sentences. There is absolutely no killer animals in the film. The only damage an animal does in the film is a small scratch that hardly anyone would feel if it happened to them. This is far more supernatural flick than anything, so it can be a little bit of a downer when it sets up attacks that don't come. The film also has the most annoying characters of recent times. The animals rights thing I'm okay with, but that really doesn't excuse the kinds of characters in this film. They are so retarded that I finally decided to make a comment on it. Being a person who's very tolerant of bad acting, this is bordering on the ridiculous. It's more of how stupid they react in their situation than anything. You have to see it to believe it.The Final Verdict: Bad acting and a real shocker of a plot line may be offset by some great suspense scenes and tons of gore. It may be equaled out, but that is all in the eye of the beholder. Give it a shot if you like this kind of film, you may be surprised. Just be careful that it's very hit or miss.Rated R: Graphic Violence, Graphic Language, animals in danger, and scenes of drug use

aliuk I found this a really interesting and challenging film, not like your usual run-of-the-mill horror movie. I'm not going to give anything away because I think it is worth seeing, but there were some very clever plot twists that took me completely by surprise! The acting was good, I thought that all the actors really pulled together as a team and that really shows (also the mark of a good director!). I also think the direction itself was really tight and perfect for the creepy, slightly claustrophobic nature of the scenes underground. The supernatural elements were fascinating as well, a very modern take on a popular genre. All in all a really good evening's viewing, and well worth seeing! I would say don't miss it!

Ténèbre Rarum (Dario_the_2nd) "Lethal Dose 50" is a stylish British production that deserves a view. It's a for sure a great and pleasure full time killer. The cast isn't that well known, although maybe the spice girl " Melania Brown" could be a recognizable face. The director of this horror SF flick, "Simon De Selva" sets a pretty impressive movie onto your screen as first time director! The tension is superb and of a perfect level. The director knew how to put in the suspense moments at just the right and perfect time. Acting is of a decent quality though can't be called amazing but actually I think that was for sure not needed into this flick. Everyone played their part to best of their ability and in which they succeeded for sure. Sometimes I did spot some "28 Days Later" links into the film but it never annoyed me in anyway. It didn't interfere into this flick in a negative way. The music is good and adds by times that certain needed drive to get some scenes, even the whole movie into a certain gear so it starts rolling onto your screen and creates that great feeling of being locked onto your screen. Which also gives that extra power onto these "jump chair" scenes. Where into this movie one is to be found for sure!Not as great as "28 Days Later" but for sure much better as "Dogsoldiers"! A' kinda must see if you're in for a foreign filled film evening.Dario/ 7.5 outa 10.