The Rat Patrol uses Moffitt's old flame as a guide to rescue her husband, a French rocket scientist, from the Germans.

A lieutenant is infiltrated by submarine to set up naval gunfire coordinates, but Troy gets suspicious when the officer appears more interested in mapping the Allied positions than the German ones.

A British general is rescued in the desert. He insists upon leading the Rat Patrol on a mission to disrupt a German oil pipeline, despite his deteriorated condition.

Troy hides aerial photographs of secret German installations before being captured by the Gestapo. Then a street urchin finds and tries to sell the photos.

Moffitt gets into a German-held lighthouse by posing as an electrician, to try to gain information about a German naval convoy headed for North Africa which is carrying Tiger tanks.

A British colonel is captured by the Germans after attending a staff meeting which centered on an upcoming Allied offensive. The Rat Patrol is ordered to either rescue or kill him before he can be interrogated. His Sikh aide insists on participating in the mission.

Dietrich traps the Rat Patrol in a cellar. In the cellar are a pregnant woman who has a valuable map, and a resistance fighter who has a personal vendetta with the woman.

Lieutenant West is on his way to stop a medical supply convoy, when he's ambushed by an Afrika Korps patrol. Wounded and rescued by Moffatt and Pettigrew, before he dies he informs them that he's got to stop the medical supplies, as some are poisonous. When Moffatt destroys the deadly supplies he is put under arrest by a British Army Major.

The young mute son of British General Simms is kidnapped in a commando raid by Dietrich and taken to Rhodes. The patrol must rescue the boy from the island's garrison with only the help of one Greek resistance fighter.

Hitchcock is supervising a transport convoy of new anti-aircraft shell fuses when the convoy is attacked by a German unit. Hitchcock is wounded by a deserter.

The Patrol is ordered to rescue pop star Mickey Roberts (singer Jack Jones), who is a P.O.W. in a small Afrika Korps compound, with the S.S. also turning up to make Roberts into a propaganda coup.

En route to a meeting with an Arab agent, the patrol is ambushed by Dietrich. With the exception of Troy, they're all captured and taken to Dietrich's desert base. Troy eventually meets up with the agent, who turns out to be a teenage boy, and a female Irish teacher, but will she allow the boy to help Troy?

Troy infiltrates a German H.Q. posing as a blinded Afrika Korps officer to steal vital information.

When the patrol ambush an Afrika Korps supply column, Troy accidentally wounds a German nurse. Feeling guilty, Troy decides to take her to a German field hospital. The only problem is that on the way she overhears a piece of vital information.

Troy determines that the Rat Patrol's only chance to destroy a supply depot inside an enemy-held fortress is by capturing a German tank and using it to get past the guards.

The Patrol attempts to destroy a small village that currently has a train in it that the Germans are loading with ammunition. However, there is a small group of Arabs (including women and children) being used to load the ammunition. One of the women stumbles upon Troy and offers to help by warning her people. But as Troy attempts to plant the explosives, Dietrich catches on to the plan and gives alarm. Troy ends up shot and captured. It is now up to the rest of the Patrol to cause enough diversion to get him free. The woman continues to plead with Dietrich to give Troy medical attention. As Dietrich is questioning Troy, though, Troy breaks free, shoots the German and is able—with the Arab woman's father's help—to get the explosives planted. The train goes up; the man is killed.

The Patrol ambushes a German courier and finds that his papers contain charts showing desert waterholes and some oases which are unknown to the Allies or the Germans. Suddenly a German patrol attacks, wounding Tully and destroying the Patrol's jeeps, water and weapons. Troy and crew strike out for a waterhole mentioned on the chart. Hours later, near their end, Troy and his men stagger toward an inviting waterhole to find it has been poisoned. On a distant dune they see Dietrich. Tully is near the end, because of his wound. It is up to Troy to negotiate with Dietrich.

Captain Dietrich monitors a broadcast sent to the Patrol from HQ and then intercepts them on their way to meet and escort a supply convoy. With the odds decidedly against the Rats, Troy takes refuge in an oasis. A child, playing nearby, runs away terrified of the noise and falls down an old well. The Allies and the Nazis agree to put the war on hold and work together to get the child (who is still alive) out. A second German unit appears and shoots Tully. In the end, they are able to rescue the child and, in the confusion, the Patrol escapes.