Aquaman, Wonder Woman, and Superman are swept away by a tornado and magically transported to a Wizard of Oz planet, courtesy of Mxyzptlk. Superman is changed into the Tinman, Wonder Woman into the Cowardly Lion, and Aquaman into the Scarecrow. After battles with crazy foes in the strange land, it's the quick-thinking Superman that sends Mxyzptlk back to the fifth dimension, and the Superfriends back home.

Superman, Batman, Robin, and Wonder Woman fight against Dr. Frankenstein and his creatures. The final product of his experiments results in a evil and terrifying monster made up of the powers belonging to Superman, Batman, and Wonder Woman. Drained of their strength and powers, these Superfriends are no match for the monster. So they combine all their remaining strength and channel it into Robin, who becomes a strong and flying Super Robin. Knowing both he and the monster have the same strengths and weaknesses, Robin shields himself and uses Kryptonite to bring him down. All strength and powers are then returned to the Superfriends, and Dr. Frankenstein is apprehended.

Captain Nimoy demands the ransom of the world's Kryptonite or else the continents will be sunk to the ocean. With Superman and Wonder Woman on Saturn, the rest of the Superfriends recruit the Kandorians from the Fortress of Solitude to stop Nimoy and his band of thugs, which includes Andriod Batman.

Arguably the best Superfriends episode of the franchise, ""Universe of Evil"" finds Batman, Robin, Wonder Woman, and Aquaman heading to a dam that's about to crack open. But when cables are fired into the dam from the Batjet and Invisible Jet, they're pulled to help the dam break wide open, creating title waves into near-by villages. We then learn that these are evil Superfriends, or Super Enemies, in a parallel universe. Soon after, both the evil Superman and our good Superman fly to Mount Vesuvious in their respected universes. The sinister villain attempts to cause the volcano to erupt, while our hero tries to prevent the eruption. The evil Superman succeeds, but the eruption sends each Superman into the opposite universe.While the good Superman is hampered and captured by the Super Enemies and locked away at the Hall of Evil, the evil Superman soon realizes what has happened and attempts to take over the good universe. Our Superman escapes and is aided by a scientist at Metropolis Un

The Wonder Twins and Gleek see trolls running out of a cave during a camping trip. They go to where the trolls are coming from and wind up in Middle Earth, where Zan and Jayna are captured and turned into trolls by the evil wizard Malhavoc, who has enslaved other trolls. Although Gleek summons the other Superfriends to rescue the Wonder Twins and free the trolls, Malhavoc stops them and turns them into trolls (except Gleek). Wonder Woman and Batman escape with the troll's leader and get to a ring that can help defeat Malhavoc. They are successful, the Superfriends ane un-trolled, and the rest of the trolls are free. Suddenly, Gleek wakes up, discovering it's all a dream. Or so he thinks, as he sees another small shadow in the forest...

After Superman stops a radioactive meteorite from crashing into a prehistoric planet, the blast sends Superman to the medievil planet of Camelon with no memory due to the radioactive particles in the meteor. A group of invaders led by Logan find Superman and cause him to think that he's the Black Knight and plan to use him to overthrow Arthur 7 (the planet's version of King Arthur) and take over Camelon. The other Superfriends arrive to help Arthur 7, only to be captured. After escape, it's a joust with Batman that returns Superman's memory, and all's well that ends well on Camelon.

In an attempt to take over the world, Lex Luthor calls on the help of strange solar creatures from the sun. Lex successfully imprisons all the Superfriends (except the Wonder Twins, who are vacationing on their home planet Exxor), as the solar cretaures turn the sun from yellow to red. The yellow rays of the sun gives Superman his powers, so the red sun makes him no stronger than the average human. However, the solar creaturs have their own agenda and beging to torch the entire planet, and leave Lex to die. In an act of desperation, Lex releases the Superfriends so they can get rid of the solar creatures and return them to the sun. Lex is then captured by the Superfriends.

Thieves on an Arabian-like planet have stolen a magic lamp and accidentally drop it on Earth. The Wonder Twins find it and they end up getting captured as well as the Hall of Justice being demolished. The other Superfriends successfuly stop the thieves and the controlled genie from ruling the planet and save the Wonder Twins.