Bull helps an agoraphobic client bring a wrongful death suit against the alleged killer of his beloved aunt, but the client’s inability to testify in person threatens the trial. Also, Taylor forges a connection with TAC’s agoraphobic client, and Chunk’s new relationship hits a snag when his mother, Adaline, visits.

Bull helps his friend, Army psychiatrist Colonel Victor Taggert, mount a diminished capacity defense for a sergeant accused of killing a fellow soldier. Also, Marissa forges a romantic connection with her art dealer, Henri Fray, a French gallery owner in need of legal assistance to stop an auction house from selling a piece of art that should be repatriated.

The TAC team gets a rare glimpse into Bull’s personal life when his estranged brother of 13 years, Jacob Bull, unexpectedly arrives in New York. Also, TAC represents a financial investor accused by the FBI of running a Ponzi scheme with his father to defraud their clients of millions of dollars.

The TAC team finds itself in a tense and unprecedented situation when Bull faces off against Marissa and her new boss in court, following her departure from the company. Also, Taylor's professional life works against her during her custody battle with her ex-husband.

Bull and Chunk aim to prove that their client, a woman on trial for murder, committed the crime due to a lack of behavioral control caused by a brain tumor; Taylor is suspected by the FBI of committing cybercrimes.

Bull helps a grieving mother, Vernice, sue the developers of a computer program that misidentified her son as a criminal, leading him to be fatally shot by the police. Also, Bull and Marissa clash when she considers a job offer from a rival company.

Bull needs a Christmas miracle when he takes on a sports agency’s young assistant charged with providing a star client lethal drugs.

Bull’s legal troubles go from professional to personal when new evidence in his bribery trial implicates his wife, Izzy. Also, the TAC team’s efforts to assist Bull in court are thwarted by his attorney, who fears they will cross a legal line to help their boss.

Bull and the TAC team are under pressure when they have just two days to prepare a defense for a midwife accused of practicing without a license. With time running out, the team tries to convince the private religious community of women their client helps to serve as character witnesses.

The TAC team asks Bull to step aside, when they fear his recent issues could negatively affect their defense of a business mogul accused of being mentally unfit to lead his company.

Bull faces uncertainty in court, when TAC handles a class action suit against a vaping company selling malfunctioning devices, and the trial outcome hinges on just one juror. Marissa takes the initiative when Bull ignores TAC’s growing financial difficulties.

Bull contends with a biased jury pool when TAC represents a man charged with his high school girlfriend’s murder after a docuseries depicts him as the prime suspect in the decades-old homicide.

TAC’s defense strategy for a client on trial for going public with classified governments under the Espionage Act is compromised when Bull experiences emotional turmoil following his daughter’s kidnapping. As Bull grows increasingly agitated, the team faces a difficult time in court when federal law leaves them unable to tell jurors their client’s motive for leaking the sensitive information.

Bull and the TAC team must call upon all their collective experience to locate Bull’s kidnapped daughter, and the abductor warns them not to go to the police. As Bull works to build the most important psych profile of his life, he begins to suspect the captor is someone connected to his past.